2014•Drug Metabolism and PharmacokineticsRequires access

In vitro glucuronidation of the primary metabolite of 10-chloromethyl-11-demethyl-12-oxo-calanolide A by human liver microsomes and its interactions with UDP-glucuronosyltransferase substrates

Xin Liu, Sheng Li, Manman Zhao, Jiaqi Mi, Zhihao Liu, Yan Li

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Key concepts: Glucuronidation, UGT2B7, Microsome, Chemistry, Metabolite, Glucuronide, Glucuronosyltransferase, Pharmacology

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In vitro glucuronidation of the primary metabolite of 10-chloromethyl-11-demethyl-12-oxo-calanolide A by human liver microsomes and its interactions with UDP-glucuronosyltransferase substrates — Research Paper | ScholarLens