2017•European Journal of Drug Metabolism and PharmacokineticsRequires access

Identification of Uridine 5′-Diphosphate-Glucuronosyltransferases Responsible for the Glucuronidation of Mirabegron, a Potent and Selective β3-Adrenoceptor Agonist, in Human Liver Microsomes

Kentaro Konishi, Daisuke Tenmizu, Shin Takusagawa

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Key concepts: UGT2B7, Glucuronidation, Uridine diphosphate, Chemistry, Glucuronosyltransferase, Microsome, Glucuronide, Mefenamic acid

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Identification of Uridine 5′-Diphosphate-Glucuronosyltransferases Responsible for the Glucuronidation of Mirabegron, a Potent and Selective β3-Adrenoceptor Agonist, in Human Liver Microsomes — Research Paper | ScholarLens