2004•Journal of Biomaterials Science Polymer EditionRequires access

Preparation and characterization of pH-sensitive hydrogel of chitosan/poly(acrylic acid) co-polymer

Lili Shi, Liming Yang, Jie Chen, Yong Pei, Min Chen, Baojun Hui, Jian Li

Abstract

A pH-sensitive co-polymer hydrogel of chitosan/poly(acrylic acid) (CS/PAAc) was prepared by irradiating the aqueous solution mixture of chitosan and acrylic acid with 60Co gamma-ray irradiation. The effect of the composition of chitosan and AAc on the properties of the hydrogel, such as swelling ratio and pH-sensitivity, were determined. Fourier Transform Infrared (FT-IR) spectrometry was applied in the attenuated total reflectance (ATR) mode for analyzing the structure change of the hydrogels after the treatment in different pH buffer solutions.

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Key concepts: Chitosan, Acrylic acid, Self-healing hydrogels, Swelling, Polymer, Attenuated total reflection, Aqueous solution, Fourier transform infrared spectroscopy