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Direct Isocoumarin Synthesis Through LDA-Promoted Addition of Acetaldehyde on Orsellinate. An Abrupt Synthesis of 6-Hydroxymellein, a Fungal Phytotoxin

Michel Barbier, Michel Devys

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Abstract

The LDA-promoted addition of acetaldehyde on orsellinate gives (±) 6 -hydroxymellein, a fungal phytotoxin, with a 51% yield.

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What this paper is about

The LDA-promoted addition of acetaldehyde on orsellinate gives (±) 6 -hydroxymellein, a fungal phytotoxin, with a 51% yield.

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OpenAlex reports 6 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The LDA-promoted addition of acetaldehyde on orsellinate gives (±) 6 -hydroxymellein, a fungal phytotoxin, with a 51% yield.

Key concepts: Isocoumarin, Phytotoxin, Chemistry, Acetaldehyde, Yield (engineering), Organic chemistry, Biochemistry, Toxin

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Direct Isocoumarin Synthesis Through LDA-Promoted Addition of Acetaldehyde on Orsellinate. An Abrupt Synthesis of 6-Hydroxymellein, a Fungal Phytotoxin — Research Paper | ScholarLens