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1989•Annals of NeurologyRequires access

AIDS‐related vacuolar myelopathy is not associated with coinfection by human T‐lymphotropic virus Type I

Bruce J. Brew, William D. Hardy, Evelyn E. Zuckerman, Nancy Chien, Morris Paul, Marc K. Rosenblum, Håkan Gadler, Anders Vahlne, Jonathan Gold, Donald A. Armstrong, Richard W. Price

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Abstract

Assessment of antibodies against human T-lymphotropic virus type I (HTLV-I) by enzyme-linked immunoassay, immunofluorescence, and Western blot was undertaken in patients with pathologically or clinically diagnosed acquired immunodeficiency syndrome-related vacuolar myelopathy to determine whether this retrovirus could be etiologically implicated in this disorder. No serological evidence for HTLV-I was found in the patients with vacuolar myelopathy, though 1 patient with an atypical myelopathy did have antibodies against HTLV-I.

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What this paper is about

Assessment of antibodies against human T-lymphotropic virus type I (HTLV-I) by enzyme-linked immunoassay, immunofluorescence, and Western blot was undertaken in patients with pathologically or clinically diagnosed acquired immunodeficiency syndrome-related vacuolar myelopathy to determine whether this retrovirus could be etiologically implicated in this disorder. No serological evidence for HTLV-I was found in the patients with vacuolar myelopathy, though 1 patient with an atypical myelopathy did have antibodies against HTLV-I.

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Available abstract

Assessment of antibodies against human T-lymphotropic virus type I (HTLV-I) by enzyme-linked immunoassay, immunofluorescence, and Western blot was undertaken in patients with pathologically or clinically diagnosed acquired immunodeficiency syndrome-related vacuolar myelopathy to determine whether this retrovirus could be etiologically implicated in this disorder. No serological evidence for HTLV-I was found in the patients with vacuolar myelopathy, though 1 patient with an atypical myelopathy did have antibodies against HTLV-I.

Key concepts: Myelopathy, Coinfection, Human T-lymphotropic virus, Immunofluorescence, Virology, Serology, Medicine, Retrovirus

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AIDS‐related vacuolar myelopathy is not associated with coinfection by human T‐lymphotropic virus Type I — Research Paper | ScholarLens