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1973•Journal of Radiation ResearchOpen access

Serum Levels of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) in Subjects Accidentally Exposed to 192Ir Gamma rays

Koichi Wakabayashi, Koichiro Isurugi, Bun-ichi Tamaoki, S. Akaboshi

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Abstract

Serum levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were determined by radioimmunoassay in 6 subjects who had been exposed accidentally to 192Ir gamma rays. All subjects showed normal levels of LH and FSH shortly after the irradiation. From 100 to 150 days post-irradiation, however, serum FSH levels increased in subjects who received 12.2 rad or more, a finding in agreement with the decrease in sperm concentration below 10 millions/ml, while in the other 2 subjects who received 9.8 and 10.9 rad, it remained within normal range. The elevation in serum FSH levels in one of the severely exposed subjects (Y. S.) was noted as late as 413 days after the exposure, while the hormone levels in the all other cases declined toward normal level.

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Serum levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were determined by radioimmunoassay in 6 subjects who had been exposed accidentally to 192Ir gamma rays. All subjects showed normal levels of LH and FSH shortly after the irradiation. From 100 to 150 days post-irradiation, however, serum FSH levels increased in subjects who received 12.2 rad or more, a finding in agreement with the decrease in sperm concentration below 10 millions/ml, while in the other 2 subjects who received 9.8 and 10.9 rad, it remained within normal range. The elevation in serum FSH levels in one of the severely exposed subjects (Y. S.) was noted as late as 413 days after the exposure, while the hormone levels in the all other cases declined toward normal level.

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Available abstract

Serum levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were determined by radioimmunoassay in 6 subjects who had been exposed accidentally to 192Ir gamma rays. All subjects showed normal levels of LH and FSH shortly after the irradiation. From 100 to 150 days post-irradiation, however, serum FSH levels increased in subjects who received 12.2 rad or more, a finding in agreement with the decrease in sperm concentration below 10 millions/ml, while in the other 2 subjects who received 9.8 and 10.9 rad, it remained within normal range. The elevation in serum FSH levels in one of the severely exposed subjects (Y. S.) was noted as late as 413 days after the exposure, while the hormone levels in the all other cases declined toward normal level.

Key concepts: Luteinizing hormone, Follicle-stimulating hormone, Internal medicine, Endocrinology, Radioimmunoassay, Hormone, Medicine, Gonadotropic cell

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Serum Levels of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) in Subjects Accidentally Exposed to 192Ir Gamma rays — Research Paper | ScholarLens