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2011•Biophysical ChemistryOpen access

Osmolyte effects on protein stability and solubility: A balancing act between backbone and side-chains

Matthew Auton, Jörg Rösgen, Mikhail Sinev, Luis Marcelo F. Holthauzen, D. Wayne Bolen

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Key concepts: Osmolyte, Chemistry, Protein stability, Side chain, Solubility, Random coil, Crystallography, Polarizability

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