The B Vitamins: Riboflavin and Nicotinic acid

In the last article we saw how Goldberger, in 1926, demonstrated that the ‘Water soluble B’ factor of McCollum and Davies contained more than one vitamin. He showed that pellagra was associated with the lack of a vitamin and that the latter was distributed in a somewhat similar manner to the anti‐beri‐beri factor. However, Goldberger demonstrated that there was an essential difference between the two factors: the one preventing pellagra was more stable to heat. He called it the pellagra‐preventive, or P‐P factor.