ACUTE HEPATITIS B IN INFANTS BORN TO HBsAg ASYMPTOMATIC CARRIER MOTHERS
Gian Alessandro Moroni, C Chiccoli, Alessandro Remo Zanetti, Maria Teresa Angeli, Anna Maria Giunta
Abstract
Gian Alessandro Moroni, C Chiccoli, Alessandro Remo Zanetti, Maria Teresa Angeli, Anna Maria Giunta
Abstract
Within an eight-month period, five cases of acute hepatitis B were observed in children born to asymptomatic HBsAg carrier mothers. At delivery, four mothers were HBeAg-positive and one was anti-HBe-positive. At an average age of 17+/-3 weeks the infants showed high transaminases levels and appearance of markers of HBV infection. Three children became HBsAG chronic carriers, one had a brief HBsAg-antigenemia (1 week), while the last one showed clinical and biochemical signs of hepatitis B in absence of detectable HBsAg but with anti-HBc and anti-HBe (window phase) and later became anti-HBs-positive.
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Within an eight-month period, five cases of acute hepatitis B were observed in children born to asymptomatic HBsAg carrier mothers. At delivery, four mothers were HBeAg-positive and one was anti-HBe-positive. At an average age of 17+/-3 weeks the infants showed high transaminases levels and appearance of markers of HBV infection. Three children became HBsAG chronic carriers, one had a brief HBsAg-antigenemia (1 week), while the last one showed clinical and biochemical signs of hepatitis B in absence of detectable HBsAg but with anti-HBc and anti-HBe (window phase) and later became anti-HBs-positive.
Key concepts: Medicine, HBsAg, HBeAg, Asymptomatic, Asymptomatic carrier, Hepatitis B, Hepatitis, Pediatrics