1980•Pure and Applied ChemistryOpen access

The biosynthesis of polyketide-derived mycotoxins

P. S. STEYN

Abstract

The biosynthesis of a few representativepolyketide-derived mycotoxins is reviewed viz.patulin, citrinin, diplosporin, ochratoxin A, maltoryzine, xanthomegnin, cytochalasans, ergochromes, zearalenone, citreoviridin, and the aflatoxins.Particular attention is given to the conversion:acetate + averufin -- versiconal acetate -'-versicolorin A -* sterigmatocystin -'-aflatoxin B1.

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Key concepts: Sterigmatocystin, Patulin, Citrinin, Chemistry, Polyketide, Aflatoxin, Mycotoxin, Ochratoxin A