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2011•Virus GenesOpen access

Mutations in the spike gene of porcine epidemic diarrhea virus associated with growth adaptation in vitro and attenuation of virulence in vivo

Tetsuo Sato, Natsumi Takeyama, Atsushi Katsumata, Kotaro Tuchiya, Toshiaki Kodama, Ko-ichi Kusanagi

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Key concepts: Serial passage, Vero cell, Biology, Virology, Virulence, Porcine epidemic diarrhea virus, Virus, Gene

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