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2014•Chemical CommunicationsRequires access

A highly selective water-soluble optical probe for endogenous peroxynitrite

Ji‐Ting Hou, Jin Yang, Kun Li, Ye-Xin Liao, Kang‐Kang Yu, Yongmei Xie, Xiao‐Qi Yu

Open publisher page 91 citations

Abstract

A colorimetric and fluorescent probe C-Py-1 for ONOO(-) was prepared and it could exhibit high sensitivity and excellent selectivity toward ONOO(-) among reactive oxygen species (ROS) and reactive nitrogen species (RNS) with a rapid response time in 100% water solution. Meanwhile, C-Py-1 was successfully applied in the imaging of endogenous ONOO(-) in RAW264.7 cells.

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What this paper is about

A colorimetric and fluorescent probe C-Py-1 for ONOO(-) was prepared and it could exhibit high sensitivity and excellent selectivity toward ONOO(-) among reactive oxygen species (ROS) and reactive nitrogen species (RNS) with a rapid response time in 100% water solution. Meanwhile, C-Py-1 was successfully applied in the imaging of endogenous ONOO(-) in RAW264.7 cells.

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OpenAlex reports 91 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A colorimetric and fluorescent probe C-Py-1 for ONOO(-) was prepared and it could exhibit high sensitivity and excellent selectivity toward ONOO(-) among reactive oxygen species (ROS) and reactive nitrogen species (RNS) with a rapid response time in 100% water solution. Meanwhile, C-Py-1 was successfully applied in the imaging of endogenous ONOO(-) in RAW264.7 cells.

Key concepts: Peroxynitrite, Reactive nitrogen species, Endogeny, Chemistry, Reactive oxygen species, Fluorescence, Selectivity, Biophysics

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