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2006•Biochemical Society TransactionsRequires access

Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species

Guy C. Brown, Vilmantė Borutaitė

Open publisher page 58 citations

Abstract

ROS (reactive oxygen species) and RNS (reactive nitrogen species) are central to the innate immunity that protects us from infection, but also contribute to degenerative diseases and possibly aging. However, ROS and RNS are increasingly recognized to contribute to physiological signalling. This review briefly describes the main interactions between ROS and RNS and shows how their origins, chemistry, metabolism and biological actions are intimately linked.

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What this paper is about

ROS (reactive oxygen species) and RNS (reactive nitrogen species) are central to the innate immunity that protects us from infection, but also contribute to degenerative diseases and possibly aging. However, ROS and RNS are increasingly recognized to contribute to physiological signalling. This review briefly describes the main interactions between ROS and RNS and shows how their origins, chemistry, metabolism and biological actions are intimately linked.

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OpenAlex reports 58 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

ROS (reactive oxygen species) and RNS (reactive nitrogen species) are central to the innate immunity that protects us from infection, but also contribute to degenerative diseases and possibly aging. However, ROS and RNS are increasingly recognized to contribute to physiological signalling. This review briefly describes the main interactions between ROS and RNS and shows how their origins, chemistry, metabolism and biological actions are intimately linked.

Key concepts: Reactive nitrogen species, Reactive oxygen species, Nitric oxide, Chemistry, Reactive nitrogen, Oxygen, Reactive intermediate, Nitrogen

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