1959Circulation ResearchOpen access

A Continuous Cardiac Output Recorder Employing the Fick Principle

Arthur C. Guyton, FARISH CHARLES A., ABERNATHY J. BERRY

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Abstract

A continuous cardiac output recorder has been developed utilizing an oxygen consumption recorder, an arteriovenous oxygen difference recorder and a computer. The computer continuously derives and records the cardiac output by dividing the rate of oxygen consumption by the A-V oxygen difference. Calibration of the continuous cardiac output recorder against a Ludwig stromuhr showed that under many different conditions and many different levels of cardiac output the 305 individual calibration points had a mean deviation from the regression line of ± 7.7 per cent. This correlation is as satisfactory as previously reported correlations between the intravenous dye method for recording cardiac output and the direct Fick method.

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A continuous cardiac output recorder has been developed utilizing an oxygen consumption recorder, an arteriovenous oxygen difference recorder and a computer. The computer continuously derives and records the cardiac output by dividing the rate of oxygen consumption by the A-V oxygen difference. Calibration of the continuous cardiac output recorder against a Ludwig stromuhr showed that under many different conditions and many different levels of cardiac output the 305 individual calibration points had a mean deviation from the regression line of ± 7.7 per cent. This correlation is as satisfactory as previously reported correlations between the intravenous dye method for recording cardiac output and the direct Fick method.

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Available abstract

A continuous cardiac output recorder has been developed utilizing an oxygen consumption recorder, an arteriovenous oxygen difference recorder and a computer. The computer continuously derives and records the cardiac output by dividing the rate of oxygen consumption by the A-V oxygen difference. Calibration of the continuous cardiac output recorder against a Ludwig stromuhr showed that under many different conditions and many different levels of cardiac output the 305 individual calibration points had a mean deviation from the regression line of ± 7.7 per cent. This correlation is as satisfactory as previously reported correlations between the intravenous dye method for recording cardiac output and the direct Fick method.

Key concepts: Cardiac output, Fick principle, Arteriovenous oxygen difference, Calibration, Oxygen, Heart rate, Biomedical engineering, Mathematics

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