2009•Bioorganic & Medicinal Chemistry LettersOpen access

Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11β-HSD1 inhibitors

Yosup Rew, Dustin L. McMinn, Zhulun Wang, Xiaodong He, Randall W. Hungate, Juan C. Jaén, Athena Sudom, Daqing Sun, Hua Tu, Stefania Ursu, Elisia Villemure, Nigel P.C. Walker, Xuelei Yan, Qiuping Ye, Jay P. Powers

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Key concepts: Benzamide, Chemistry, In vivo, Stereochemistry, Combinatorial chemistry, Selectivity, Biochemistry, Biotechnology