2002•Journal of Labelled Compounds and RadiopharmaceuticalsRequires access
Synthesis of N‐(2,3‐dihydro‐1‐[14C]methyl‐2‐oxo‐5‐phenyl‐1H‐1,4‐benzodiazepin‐3‐yl)‐benzamide and N‐(2,3‐dihydro‐1‐[14C]methyl‐2‐oxo‐5‐phenyl‐1H‐1,4‐benzodiazepin‐3‐yl)‐N‐[14C]methyl‐benzamide as novel carbon‐14 labelled CCK antagonists
Hojatollah Matloubi, Ali Khalaj, Reza Dowlatabadi, Gholamhossein Shirvani
Open publisher page 6 citations
Abstract
Abstract Two benzodiazepine CCK antagonists N‐(2,3‐dihydro‐1‐[14C]methyl‐2‐oxo‐5‐phenyl‐1H 1,4‐benzodiazepin‐3‐yl)‐benzamide 2 and N‐(2,3‐dihydro‐1‐[14C]methyl‐2‐oxo‐5‐phenyl‐1H‐1,4‐benzodiazepin‐3‐yl)‐[14C]methyl‐benzamide 3 were synthesized in high yields through the reaction of N‐(2,3‐dihydro‐2‐oxo‐5‐phenyl‐1H‐1,4‐benzodiazepin‐3‐yl)‐benzamide 1 with [14C] methyl iodide in different situations. Copyright © 2002 John Wiley & Sons, Ltd.