2008•Natural Product ResearchRequires access

Effect of ethyl acetate extract fromMarchantia convolutaon inhibition of human liver carcinoma HepG2 cells

Hui Cao, Jing Chen, Bo‐Ping Tang, Ming Xu

Abstract

The effect of the dichloromethane fraction (DF) of the ethyl acetate extract from Marchantia convoluta on the inhibition of human liver carcinoma cell line HepG2 was investigated. DF can remarkably induce HepG2 cell apoptotic, accompanied by a decrease of the cell viability and an increase of the fraction of S-phase cells by 62.5% in a concentration-dependent manner.

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Key concepts: Ethyl acetate, Chemistry, Apoptosis, Cell culture, Hepatic carcinoma, Dichloromethane, Fraction (chemistry), Biochemistry