2008•HaematologicaOpen access

The Janus kinase 2 (JAK2) V617F mutation in Chinese patients with chronic myeloproliferative disorders

Zhijian Xiao, Jennifer Zhang, L. Li, Ling Nie, Ling Yang, Shicai Xu

Abstract

A single, valinetophenylalanine somatic mutation at position 617 (V617F) in the JAK2 kinase in patients with chronic myeloproliferative diseases (cMPDs) were reported.[1][1]–[4][2] In the present study, the JAK2 V617F mutation was detected in a larger cohort of Chinese cMPDs patients, to evaluate

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Key concepts: JAK2 V617F, Myeloproliferative Disorders, Janus kinase 2, Mutation, Janus kinase, Medicine, Janus, Cancer research