1991•Acta Orthopaedica ScandinavicaOpen access

Heterogeneity of xenografted osteosarcoma: A human sarcoma transplanted into nude mice

Emilio Delgado‐Baeza, C. Miralles-Flores, Weida Gonzalez-Medievo

Abstract

Human osteoblastic osteosarcoma transplanted into nude mice developed two different subtypes of non-osteogenic sarcoma: one solid and the other cystic. This could reflect the heterogeneity of osteoblastic osteosarcoma; various tumor regions have different characteristics.

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Key concepts: Osteosarcoma, Sarcoma, Medicine, Nude mouse, Cancer research, Pathology, Transplantation, Internal medicine