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Typing for HLA‐D Determinants. Comparison of Typing Results using Homozygous Stimulating Cells and Primed Cultures

Henry Hirschberg, Aulikki Kaakinen, Erik Thorsby

Open publisher page 32 citations

Abstract

Typing for HLA-D determinants, using primed lymphocyte typing (PLT), has been compared to the results obtained using conventional homozygous stimulating cell primary MLC tests. The HLA-Dwl, -Dw2 and -Dw3 specificities were studied. Preliminary results indicate that these two methods essentially type for the HLA-D determinants and that reproducible results can be obtained employing the PLT technique after 24 hours of incubation in the secondary cultures.

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What this paper is about

Typing for HLA-D determinants, using primed lymphocyte typing (PLT), has been compared to the results obtained using conventional homozygous stimulating cell primary MLC tests. The HLA-Dwl, -Dw2 and -Dw3 specificities were studied. Preliminary results indicate that these two methods essentially type for the HLA-D determinants and that reproducible results can be obtained employing the PLT technique after 24 hours of incubation in the secondary cultures.

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Available abstract

Typing for HLA-D determinants, using primed lymphocyte typing (PLT), has been compared to the results obtained using conventional homozygous stimulating cell primary MLC tests. The HLA-Dwl, -Dw2 and -Dw3 specificities were studied. Preliminary results indicate that these two methods essentially type for the HLA-D determinants and that reproducible results can be obtained employing the PLT technique after 24 hours of incubation in the secondary cultures.

Key concepts: Typing, Biology, Human leukocyte antigen, Histocompatibility Testing, Microbiology, Genetics, Virology, Antigen

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Typing for HLA‐D Determinants. Comparison of Typing Results using Homozygous Stimulating Cells and Primed Cultures — Research Paper | ScholarLens