1995New England Journal of MedicineRequires access

Polycystic Ovary Syndrome

Stephen Franks

Open publisher page 2,473 citations

Abstract

Polycystic ovary syndrome — in its most typical form, the association of hyperandrogenism and chronic anovulation — is one of the most common endocrine disorders. The clinical and biochemical features are heterogeneous, and there has been much debate as to whether it represents a single disorder or several. In recent years, it has become apparent that the polycystic ovary syndrome not only is the most frequent cause of anovulation and of hirsutism, but is also associated with a characteristic metabolic disturbance (resistance to the action of insulin) that may have important implications for long-term health.DefinitionThe most widely accepted . . .

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What this paper is about

Polycystic ovary syndrome — in its most typical form, the association of hyperandrogenism and chronic anovulation — is one of the most common endocrine disorders. The clinical and biochemical features are heterogeneous, and there has been much debate as to whether it represents a single disorder or several. In recent years, it has become apparent that the polycystic ovary syndrome not only is the most frequent cause of anovulation and of hirsutism, but is also associated with a characteristic metabolic disturbance (resistance to the action of insulin) that may have important implications for long-term health.DefinitionThe most widely accepted . . .

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Available abstract

Polycystic ovary syndrome — in its most typical form, the association of hyperandrogenism and chronic anovulation — is one of the most common endocrine disorders. The clinical and biochemical features are heterogeneous, and there has been much debate as to whether it represents a single disorder or several. In recent years, it has become apparent that the polycystic ovary syndrome not only is the most frequent cause of anovulation and of hirsutism, but is also associated with a characteristic metabolic disturbance (resistance to the action of insulin) that may have important implications for long-term health.DefinitionThe most widely accepted . . .

Key concepts: Polycystic ovary, Anovulation, Medicine, Hyperandrogenism, hirsutism, Insulin resistance, Endocrine system, Ovary

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