2009•Zhongguo Yike Daxue xuebaoRequires access
Relationship between the level of serum uric acid and Alzheimer's disease.
Xiuli Shang, Fengying Zhang, Meng LingHui, Wei Zhang, Meiqing Lin, Yixue Xue
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Abstract
Objective To assess the relationship between the level of serum uric acid and Alzheimer’s disease (AD). Methods Thirty patients with AD and 30 normal control subjects were included. The level of serum uric acid was measured. Results The level of serum uric acid in AD patients was significantly lower than that in normal control subjects(P 0.05). The level of serum uric acid in male normal control subjects was significantly higher than that in female (P 0.05). No significant difference in the level of serum uric acid was found between male and female AD patients (P 0.05). Conclusion The decreased level of serum uric acid might be concerned with the pathogenesis of AD.