[Microalbuminuria in a Population of 653 Type-1 and Type-2 Diabetic-patients]
Olivier Descamps, Martin Buysschaert, Jean‐Marie Ketelslegers, Michel Hermans, Ae. Lambert
Abstract
Olivier Descamps, Martin Buysschaert, Jean‐Marie Ketelslegers, Michel Hermans, Ae. Lambert
Abstract
The aim of this retrospective study was to evaluate the prevalence of microalbuminuria in type 1 and 2 diabetic patients with or without high blood pressure levels. 653 patients were involved in the study [type 1 : n = 413 (normotensive : n = 298 ; hypertensive : n = 115) ; type 2 : n = 240 (normotensive : n = 93 ; hypertensive : n = 147)]. In type 1 diabetic patients, the prevalence of microalbuminuria was of 21 per cent. Microalbuminuria was also found in 28 per cent of type 2 diabetic subjects (p < 0,10 vs type 1). The prevalence of microalbuminuria was significantly higher in hypertensive than in normotensive diabetic subjects (28 vs 20 per cent ; p < 0,05). Blood pressure in type 1 and 2 normotensive patients was significantly higher in subjects with than without microalbuminuria. We also observed higher HbA1 levels in microalbuminuric type 1 diabetic patients. Finally, we also assessed that the prevalence of diabetic chronic complications was higher in type 1 patients with than without microalbuminuria (p < 0,05). This relationship was not evidenced in type 2 diabetic patients. In conclusion, the prevalence of microalbuminuria in a population of type 1 and 2 diabetic patients is high. We confirm in this study the relationship between microalbuminuria, blood pressure, and HbA1.
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The aim of this retrospective study was to evaluate the prevalence of microalbuminuria in type 1 and 2 diabetic patients with or without high blood pressure levels. 653 patients were involved in the study [type 1 : n = 413 (normotensive : n = 298 ; hypertensive : n = 115) ; type 2 : n = 240 (normotensive : n = 93 ; hypertensive : n = 147)]. In type 1 diabetic patients, the prevalence of microalbuminuria was of 21 per cent. Microalbuminuria was also found in 28 per cent of type 2 diabetic subjects (p < 0,10 vs type 1). The prevalence of microalbuminuria was significantly higher in hypertensive than in normotensive diabetic subjects (28 vs 20 per cent ; p < 0,05). Blood pressure in type 1 and 2 normotensive patients was significantly higher in subjects with than without microalbuminuria. We also observed higher HbA1 levels in microalbuminuric type 1 diabetic patients. Finally, we also assessed that the prevalence of diabetic chronic complications was higher in type 1 patients with than without microalbuminuria (p < 0,05). This relationship was not evidenced in type 2 diabetic patients. In conclusion, the prevalence of microalbuminuria in a population of type 1 and 2 diabetic patients is high. We confirm in this study the relationship between microalbuminuria, blood pressure, and HbA1.
Key concepts: Microalbuminuria, Medicine, Internal medicine, Blood pressure, Population, Type 2 diabetes, Diabetes mellitus, Endocrinology