2007•PubMedRequires access

[Studies on chemical constituents in herb of Centella asiatica].

Quan-Lin Yu, Wenyuan Gao, Yanwen Zhang, Jie Teng, Hong‐Quan Duan

Abstract

OBJECTIVE: To study the chemical constituents from Centella asiatica. METHOD: Chemical constituents were isolated by repeated column chromatography (Toyopearl HW-40C and HPLC) and their structures were elucidated on the basis of spectroscopic method. RESULT: Five compounds were identified as: docosyl ferulates (1), bayogenin (2), 3beta-6beta-23-trihydroxyolean-12-en-28-oic acid (3), 3beta-6beta-23-trihydroxyurs-12-en-28-oic acid (4), D-gulonic acid (5). CONCLUSION: All of the Compounds were isolated for the first time from C. asiatica.

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Key concepts: Centella, Chemical constituents, Herb, Chromatography, Chemistry, Column chromatography, High-performance liquid chromatography, Traditional medicine