2012Pharmaceutical biotechnologyRequires access

In Silico and Ultrahigh‐Throughput Screenings (uHTS) in Drug Discovery: An Overview

Debmalya Barh, Shoaib Ahmad, Atanu Bhattacharjee

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Abstract

This chapter contains sections titled: Introduction In Silico Pharmacology and Virtual Ligand Screening for Drug Discovery Lead Discovery Using Integrative Virtual Screening Application of Microarray Technology in HTS and Drug Discovery Chemical Proteomics for Drug Discovery and Development Target and Drug Discovery Using Lipomic Profiling Drug Discovery Using Integrative Genomics Toxicogenomics in Drug Discovery and Development HTP RNAi Screening for Targeted Drug Discovery High-Throughput Screening with Stem Cells Systems Biology in Drug Discovery Conclusion References

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What this paper is about

This chapter contains sections titled: Introduction In Silico Pharmacology and Virtual Ligand Screening for Drug Discovery Lead Discovery Using Integrative Virtual Screening Application of Microarray Technology in HTS and Drug Discovery Chemical Proteomics for Drug Discovery and Development Target and Drug Discovery Using Lipomic Profiling Drug Discovery Using Integrative Genomics Toxicogenomics in Drug Discovery and Development HTP RNAi Screening for Targeted Drug Discovery High-Throughput Screening with Stem Cells Systems Biology in Drug Discovery Conclusion References

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Available abstract

This chapter contains sections titled: Introduction In Silico Pharmacology and Virtual Ligand Screening for Drug Discovery Lead Discovery Using Integrative Virtual Screening Application of Microarray Technology in HTS and Drug Discovery Chemical Proteomics for Drug Discovery and Development Target and Drug Discovery Using Lipomic Profiling Drug Discovery Using Integrative Genomics Toxicogenomics in Drug Discovery and Development HTP RNAi Screening for Targeted Drug Discovery High-Throughput Screening with Stem Cells Systems Biology in Drug Discovery Conclusion References

Key concepts: Drug discovery, In silico, Computational biology, Toxicogenomics, Virtual screening, Profiling (computer programming), Drug, Biomarker discovery

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