2014•American journal of infectious diseases and microbiologyOpen access
Dengue Virus in the light of Medicinal Plants
Madeha Tahir, Faiza Naseer, Fiza Raza Bukhari, Sidra Mushtaq, Rida Ajmal Khan, Samra Sadiq Fatima Javed, Attiya Nazish
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Abstract
Dengue fever is caused by the mosquito-borne dengue virus (DENV) serotypes 1–4 and most common arboviral infection of humans in subtropical and tropical regions of the world. Dengue virus infections present with a spacious range of clinical signs from a mild feverish illness to a life-threatening shock syndrome. Till now there is no approved vaccine or drug against this virus. Therefore, there is a critical need of improvement of alternative elucidation for dengue. Several herbal species have been reported with anti-dengue activity, most of which are commonly used as nutritional components, have been used as antiviral, larvicidal, mosquitocidal and mosquito repellents against dengue as well. The objective of this review was to provide current approaches for the treatment and management/ prevention of dengue fever by targeting viral proteins involved in viral replication cycle and different developmental stages of mosquito.