Identification and characterization of serum miRNAs as molecular biomarkers for single and dual dengue virus infection

Dengue fever is a serious mosquito-borne viral disease caused by the dengue virus (DENV) and multiple infections by the mosquitoes could be severe and life-threatening. Currently, there is no remedy against the virus. Accurate and early detection of dengue is vital to reduce the mortality rate due to the severe type of dengue fever. This thesis identifies markers that have the potential to predict the disease. The identification of these biomarkers may aid clinicians in the prediction of patients who may progress to severe dengue so that early treatment could be undertaken to reduce the tendency of fatal dengue.