2015•Unpublished venueRequires access

Study: 4F-PCC may be beneficial over plasma in patients needing warfarin reversal for urgent surgical, invasive procedures

Tracey Walker

Abstract

Prothrombin Complex Concentrate [Human] (Kcentra) is non-inferior and superior to plasma for rapid international normalized ratio (INR) reversal and effective hemostasis in patients needing Vitamin K antagonist (VKA, eg, warfarin) reversal for urgent surgical or invasive procedures, according to a study published in The Lancet. INR is a standardized method of assessing the effects of VKA therapy commonly used by clinicians

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Available abstract

Key concepts: Medicine, Vitamin K antagonist, Prothrombin complex concentrate, Warfarin, Hemostasis, Vitamin k, Surgical procedures, Intensive care medicine