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2017•The Southwest Respiratory and Critical Care ChroniclesOpen access

Kcentra® (Prothrombin Complex Concentrate [Human]): Its indications, side effects, and contraindications

Amr Ismail

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Abstract

Patients with a high risk for thromboembolic events can be on long-term warfarin. Thesepatients need close monitoring of their INR and for signs of bleeding. Conventionally, freshfrozen plasma (FFP) is used for reversal of INR in patients with major bleeding or who needurgent surgery or invasive procedures. Kcentra is now available as an alternative to FFP forrapid reversal of INR and urgent hemostasis.

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Patients with a high risk for thromboembolic events can be on long-term warfarin. Thesepatients need close monitoring of their INR and for signs of bleeding. Conventionally, freshfrozen plasma (FFP) is used for reversal of INR in patients with major bleeding or who needurgent surgery or invasive procedures. Kcentra is now available as an alternative to FFP forrapid reversal of INR and urgent hemostasis.

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Available abstract

Patients with a high risk for thromboembolic events can be on long-term warfarin. Thesepatients need close monitoring of their INR and for signs of bleeding. Conventionally, freshfrozen plasma (FFP) is used for reversal of INR in patients with major bleeding or who needurgent surgery or invasive procedures. Kcentra is now available as an alternative to FFP forrapid reversal of INR and urgent hemostasis.

Key concepts: Medicine, Hemostasis, Warfarin, PROTHROMBIN COMPLEX, Prothrombin complex concentrate, Surgery, Prothrombin time, Coagulation

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