2001•Acta Scientiarum Naturalium Universitatis SunyatseniRequires access
EXPRESSION OF Fas LIGAND IN HUMAN COLON CANCER CELL LINES
张建军, 丁尔迅, Qiang Wang, 陈学云, 付志仁
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Abstract
To investigate the expression of Fas ligand in human colon carcinoma cell lines. Methods: A total of six human colon cancer cell lines were examined for the expression of Fas ligand mRNA and cell surface protein by using RT-PCR and flow cytometry respectively. Results: The results showed that Fas ligand mRNA was expressed in all of the six cancer cell lines and Fas ligand cell surface protein was expressed in part of them. Conclusion: These data suggest that Fas ligand was expressed, at least in part, in human colon cancer cell lines and might facilitate to escape from immune surveillance of the host.