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1987•FEMS Microbiology LettersRequires access

Effect of ammonium ions on the composition of fatty acids inStreptomyces fradiae, producer of tylosin

Aleš Vančura, Tomáš Řezanka, Jaroslav Maršálek, Ivana Vančurovǎ, Vladimír Křišťan, Gabriela Basařová

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Abstract

The regulation of fatty acid composition by ammonium ions and amino acids was studied in Streptomyces fradiae, a tylosin producer. The quantity of branched-chain fatty acids in S. fradiae cells decreased significantly in cultures cultivated in a medium containing high concentrations of ammonium ions, in which the biosynthesis of tylosin was also strongly inhibited. Amino acids stimulating the tylosin production most pronouncedly, also substantially modified the composition of cell fatty acids.

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The regulation of fatty acid composition by ammonium ions and amino acids was studied in Streptomyces fradiae, a tylosin producer. The quantity of branched-chain fatty acids in S. fradiae cells decreased significantly in cultures cultivated in a medium containing high concentrations of ammonium ions, in which the biosynthesis of tylosin was also strongly inhibited. Amino acids stimulating the tylosin production most pronouncedly, also substantially modified the composition of cell fatty acids.

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Available abstract

The regulation of fatty acid composition by ammonium ions and amino acids was studied in Streptomyces fradiae, a tylosin producer. The quantity of branched-chain fatty acids in S. fradiae cells decreased significantly in cultures cultivated in a medium containing high concentrations of ammonium ions, in which the biosynthesis of tylosin was also strongly inhibited. Amino acids stimulating the tylosin production most pronouncedly, also substantially modified the composition of cell fatty acids.

Key concepts: Streptomyces fradiae, Tylosin, Ammonium, Composition (language), Chemistry, Amino acid, Biosynthesis, Biochemistry

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Effect of ammonium ions on the composition of fatty acids inStreptomyces fradiae, producer of tylosin — Research Paper | ScholarLens