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2012•Journal of global pharma technologyRequires access

BILIRUBIN AND URIC ACID IN TRAUMATIC BRAIN INJURY

Usha Sachidananda Adiga, Vickneshwaran Vinayagam, Sanat Kumar Sen, G Thiagaragan

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Abstract

Background and Objectives: Oxidative stress is the imbalance between pro-oxidants and antioxidants.Uric acid and bilirubin,end products of purine ahd heme metabolism are important antioxidants in the serum, paradoxically act as pro-oxidants.Their role is controversial and to the best of our knowledge,there are few studies about uric acid and bilirubin levels in traumatic brain injury patients. Aim of our study is to estimate the levels of uric acid and bilirubin in TBI and correlate with the severity of the injury.

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What this paper is about

Background and Objectives: Oxidative stress is the imbalance between pro-oxidants and antioxidants.Uric acid and bilirubin,end products of purine ahd heme metabolism are important antioxidants in the serum, paradoxically act as pro-oxidants.Their role is controversial and to the best of our knowledge,there are few studies about uric acid and bilirubin levels in traumatic brain injury patients. Aim of our study is to estimate the levels of uric acid and bilirubin in TBI and correlate with the severity of the injury.

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Available abstract

Background and Objectives: Oxidative stress is the imbalance between pro-oxidants and antioxidants.Uric acid and bilirubin,end products of purine ahd heme metabolism are important antioxidants in the serum, paradoxically act as pro-oxidants.Their role is controversial and to the best of our knowledge,there are few studies about uric acid and bilirubin levels in traumatic brain injury patients. Aim of our study is to estimate the levels of uric acid and bilirubin in TBI and correlate with the severity of the injury.

Key concepts: Uric acid, Bilirubin, Oxidative stress, Traumatic brain injury, Antioxidant, Purine, Medicine, Biochemistry

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