2017•International PharmacopsychiatryRequires access

Hypnotic Effects of a Benzodiazepine Derivative A Clinical Observation

Yoshio Kudo

Open publisher page 9 citations

Abstract

A double-blind study was conducted on triazolam, using nitrazepam and placebo as control compounds; statistically significant differences were demonstrated in favor of triazolam compared with placebo and with nitrazepam in many aspects of efficacy, but there was no significant difference between triazolam and nitrazepam in the incidence of concomitant symptoms and side effects. The fact that a certain quantity of triazolam is equivalent in strength to ten times that quantity of nitrazepam suggests the high potency of the former. These data indicate that triazolam is a valuable sleep inducer, with highly-rated efficacy and safety.

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What this paper is about

A double-blind study was conducted on triazolam, using nitrazepam and placebo as control compounds; statistically significant differences were demonstrated in favor of triazolam compared with placebo and with nitrazepam in many aspects of efficacy, but there was no significant difference between triazolam and nitrazepam in the incidence of concomitant symptoms and side effects. The fact that a certain quantity of triazolam is equivalent in strength to ten times that quantity of nitrazepam suggests the high potency of the former. These data indicate that triazolam is a valuable sleep inducer, with highly-rated efficacy and safety.

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A double-blind study was conducted on triazolam, using nitrazepam and placebo as control compounds; statistically significant differences were demonstrated in favor of triazolam compared with placebo and with nitrazepam in many aspects of efficacy, but there was no significant difference between triazolam and nitrazepam in the incidence of concomitant symptoms and side effects. The fact that a certain quantity of triazolam is equivalent in strength to ten times that quantity of nitrazepam suggests the high potency of the former. These data indicate that triazolam is a valuable sleep inducer, with highly-rated efficacy and safety.

Key concepts: Triazolam, Nitrazepam, Benzodiazepine, Hypnotic, Placebo, Medicine, Anesthesia, Diazepam

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