Evaluation of Triazolam and Nitrazepam Use in Outpatient over 60 Years.

Recently, it has been reported that the side effect of benzodiazepine trends to occur frequently in aged people over 60 years.We examined how to use in outpatients over 60 years through interview by telephone.The results from 83 patients showed that triazolam led to awakening during the night in 29 cases (61.7%) out of 47.Nitrazepam was revealed in 25 cases (69.4%) out of 36.There was no significant difference between both drugs.However, rebound insomnia as impossibility to return to sleep appeared in 18 cases (62.1%) of 29 for triazolam and 2 cases (8%) of 25 for nitrazepam.The incidence of rebound insomnia was higher for triazolam.Amnesia occurred in 2 cases (5.4%) out of 37 interviewed outpatients taking triazolam but in none of the case of nitrazepam.