1958•OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)Requires access
THE MECHANISM OF DEVELOPMENT OF HEMORRHAGIC DIATHESIS IN ACUTE RADIATION SICKNESS
A. S. Petrova
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Abstract
Certain components of the blood-coagulating system which play a certain role in the development of the hemorrhagic syndrome in acute radiation sickness were studied. Experiments were carried out on rabbits irradiated with doses of 800 r and on dogs irradiated with 600 r. The qualitative and quantitative changes of the thrombocytes, retraction of the blood clot, and the blood coagulation time were studied. The results of investigations demonstrated that changes of all the indices listed occur previous to clinical manifestations of hemorrhagic diathesis and may serve as early diagnosistic and prognostic signs. The development of hemorrhages in radiation injury depend mainly on the disturbances in the blood- coagulating system and primarily, in the thrombocytic apparatus. The latter is affected from the very first hour after the irradiation. (tr-auth)