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2009•Journal of Tropical MedicineOpen access

Clinical values of cystatin C, IgG and D-dimer in the diagnosis of early diabetic nephropathy.

Dayu Chen, Yan-Ping Liu, Zeng HongYi, Liu Zhi-hua

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Abstract

Objective To evaluate the use of cystatin C(Cys-c),imunoglobulin G(IgG) and D-dimer(DD) in the early diagnosis and treatment of diabetic nephropathy.Method Mogensen of DN in accordance with sub-standard on the SDM group,EDN group,CDN group and control group in 24 hours urinary albumin excretion rate(UAER),Cys-C,IgG,DD on the control,and correlation analysis.Results EDN group and the CDN group in Cys-c,IgG and DD with the SDM group and the control group,the difference has statistical significance(P0.05),EDN and CDN group Cys-c,IgG and DD compare,the difference have statistical significance(P0.05).Cys-c,IgG and DD with UAER the correlation coefficients were 0.773,0.549 and 0.385.Conclusion Cys-C,IgG and DD can be used as markers in the early diagnosis of diabetic nephropathy.Cys-C had the highest correlation.

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What this paper is about

Objective To evaluate the use of cystatin C(Cys-c),imunoglobulin G(IgG) and D-dimer(DD) in the early diagnosis and treatment of diabetic nephropathy.Method Mogensen of DN in accordance with sub-standard on the SDM group,EDN group,CDN group and control group in 24 hours urinary albumin excretion rate(UAER),Cys-C,IgG,DD on the control,and correlation analysis.Results EDN group and the CDN group in Cys-c,IgG and DD with the SDM group and the control group,the difference has statistical significance(P0.05),EDN and CDN group Cys-c,IgG and DD compare,the difference have statistical significance(P0.05).Cys-c,IgG and DD with UAER the correlation coefficients were 0.773,0.549 and 0.385.Conclusion Cys-C,IgG and DD can be used as markers in the early diagnosis of diabetic nephropathy.Cys-C had the highest correlation.

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Available abstract

Objective To evaluate the use of cystatin C(Cys-c),imunoglobulin G(IgG) and D-dimer(DD) in the early diagnosis and treatment of diabetic nephropathy.Method Mogensen of DN in accordance with sub-standard on the SDM group,EDN group,CDN group and control group in 24 hours urinary albumin excretion rate(UAER),Cys-C,IgG,DD on the control,and correlation analysis.Results EDN group and the CDN group in Cys-c,IgG and DD with the SDM group and the control group,the difference has statistical significance(P0.05),EDN and CDN group Cys-c,IgG and DD compare,the difference have statistical significance(P0.05).Cys-c,IgG and DD with UAER the correlation coefficients were 0.773,0.549 and 0.385.Conclusion Cys-C,IgG and DD can be used as markers in the early diagnosis of diabetic nephropathy.Cys-C had the highest correlation.

Key concepts: Cystatin C, Diabetic nephropathy, Statistical significance, Medicine, Nephropathy, Internal medicine, Excretion, Urology

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Clinical values of cystatin C, IgG and D-dimer in the diagnosis of early diabetic nephropathy. — Research Paper | ScholarLens