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1971•Zeitschrift für Naturforschung BOpen access

Immunosuppressive Action in Vitro by a Bovine Spleen Extract

V. H. Morales, E García-Giralt

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Abstract

An extract from bovine spleen which has been shown to have immunosuppressive properties, inhibited the stimulation of DNA synthesis in mouse lymphocytes by phytohaemagglutinin and by allogeneic cells. It was also found that the lymphocytes from animals treated with the extract did not respond in vitro to an antigeneic stimulation.

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An extract from bovine spleen which has been shown to have immunosuppressive properties, inhibited the stimulation of DNA synthesis in mouse lymphocytes by phytohaemagglutinin and by allogeneic cells. It was also found that the lymphocytes from animals treated with the extract did not respond in vitro to an antigeneic stimulation.

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Available abstract

An extract from bovine spleen which has been shown to have immunosuppressive properties, inhibited the stimulation of DNA synthesis in mouse lymphocytes by phytohaemagglutinin and by allogeneic cells. It was also found that the lymphocytes from animals treated with the extract did not respond in vitro to an antigeneic stimulation.

Key concepts: Phytohaemagglutinin, In vitro, Spleen, Stimulation, DNA synthesis, Biology, Immunology, Chemistry

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