2004Acta Scientiarum Naturalium Universitatis SunyatseniRequires access

Pyrethroid Resistance in Anopheles

ZHOUHong-ning, NigelHill

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Abstract

The development of photo-stable synthetic pyrethroids has led to several of these products e. g. deltamethrin, permethrin,lambdacyhalothrin and alphacypermithrin etc, replacing DDT for house-spraying in some malaria control programmes during the 1990s. More importantly, pyrethroids are currently the onlypractical insecticides for impregnating bednets, and a widely promoted vector control intervention, because they are safe tohuman, highly toxicity for mosquitoes, coupled with a long-lasting residual activity in textile, and less are expensive than spraying walls for residual insecticide. They are effective in reducing child deaths, and can be better administered through a horizontal,community-based program.

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What this paper is about

The development of photo-stable synthetic pyrethroids has led to several of these products e. g. deltamethrin, permethrin,lambdacyhalothrin and alphacypermithrin etc, replacing DDT for house-spraying in some malaria control programmes during the 1990s. More importantly, pyrethroids are currently the onlypractical insecticides for impregnating bednets, and a widely promoted vector control intervention, because they are safe tohuman, highly toxicity for mosquitoes, coupled with a long-lasting residual activity in textile, and less are expensive than spraying walls for residual insecticide. They are effective in reducing child deaths, and can be better administered through a horizontal,community-based program.

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Available abstract

The development of photo-stable synthetic pyrethroids has led to several of these products e. g. deltamethrin, permethrin,lambdacyhalothrin and alphacypermithrin etc, replacing DDT for house-spraying in some malaria control programmes during the 1990s. More importantly, pyrethroids are currently the onlypractical insecticides for impregnating bednets, and a widely promoted vector control intervention, because they are safe tohuman, highly toxicity for mosquitoes, coupled with a long-lasting residual activity in textile, and less are expensive than spraying walls for residual insecticide. They are effective in reducing child deaths, and can be better administered through a horizontal,community-based program.

Key concepts: Permethrin, Deltamethrin, Indoor residual spraying, Pyrethroid, Toxicology, Mosquito control, Malaria, Anopheles stephensi

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