ScholarLens Back to search
1980•The Medical Journal of AustraliaRequires access

PRESYMPTOMATIC DETECTION OF HUNTINGTON'S DISEASE

David N. Propert

Open publisher page 14 citations

Abstract

Because of the usually late onset of Huntington's disease (HD) most sufferers have reproduced and passed the HD gene to about one half of their offspring before they themselves develop symptoms of the disease. Genetic counseling of persons at risk of HD would be greatly facilitated if the gene could be detected presymptomatically. At present, there is no suitable predictive test for HD, but many approaches currently being investigated show some promise. These approaches are reviewed and critically evaluated.

About this research paper

What this paper is about

Because of the usually late onset of Huntington's disease (HD) most sufferers have reproduced and passed the HD gene to about one half of their offspring before they themselves develop symptoms of the disease. Genetic counseling of persons at risk of HD would be greatly facilitated if the gene could be detected presymptomatically. At present, there is no suitable predictive test for HD, but many approaches currently being investigated show some promise. These approaches are reviewed and critically evaluated.

Why it matters

OpenAlex reports 14 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Because of the usually late onset of Huntington's disease (HD) most sufferers have reproduced and passed the HD gene to about one half of their offspring before they themselves develop symptoms of the disease. Genetic counseling of persons at risk of HD would be greatly facilitated if the gene could be detected presymptomatically. At present, there is no suitable predictive test for HD, but many approaches currently being investigated show some promise. These approaches are reviewed and critically evaluated.

Key concepts: Huntington's disease, Predictive testing, Disease, Offspring, Genetic testing, Medicine, Psychology, Genetic discrimination

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
PRESYMPTOMATIC DETECTION OF HUNTINGTON'S DISEASE — Research Paper | ScholarLens