Clinical analysis of pelvic lymph node metastasis in patients with stage IB2-IIA cervical cancer treated by pre-operative sensitivity enhancement of radiotherapy.

Objective To analyze the principles and its clinical significance of pelvic lymph node metastasis in patients with stageⅠB2～ⅡAcervical cancer treated by sensitivity enhancement of radiotherapy.Methods Sixty-four patients with stageⅠB2～ⅡA cervical cancer received sensitivity enhancement of radiotherapy before radical hysterectomy and pelvic lymph node dissection.According to the pathological results,lymph node metastasis sites and metastasis rate were analyzed.Results Eight cases had lymph node metastases(12.5%).Pelvic lymph node metastases had no relationship with patients′age,FIGO stage,the degree of differentiation or pathological types(P 0.05).Among 8 cases,only one group of lymph node metastasis had 6 cases(75.0%),among which 4 cases were obturator lymph nodes(66.7%),1 case was internal iliac lymph node(16.67%),and 1 case was external iliac lymph node(16.7%).Two-group lymph node metastasis had 1 case,which was internal obturator and iliac lymph node;4-group lymph node metastasis at the same time had 1 case,which were obturator-internal iliac/external iliac-inguinal lymph nodes.Conclusion Obturator lymph node was the most common metastasis site in patients with stageⅠB2～ⅡAcervical cancer after sensitivity enhancement of radiotherapy,followed by internal iliac and external iliac lymph node.Pre-operative sensitivity enhancement of radiotherapy for cervical cancer patients may reduce the rate of pelvic lymph node metastasis.