Studies on the Antibacterial Activity of the Extract of Stachysarpheta angustifolia

Objective:To investigate the scientific bases for the traditional use of stachytarpheta angustigolia.MEthods:In vitro antibacterial activity of the aqueous and ethanol extract of the plant was investigated using the agar cup plate diffustion method.Results:The ethanol extract of the plant showed antibacterial activity against Escherichia coli,Streptococcus faecalis,Shigella dysenteriae,Staphylococcus aureus(S.aureus),Salmonella sp., pseudomonas aeruginosa and Neisseria gonorthoseae,while the water extract was active against Escherichia coli,Streptococcus faecalis,Shigella dysenteriae,Staphylococcus aureus and Pseudomonas aeruginasa.The ethanol extract exhibited higher antibacterial activity than the water extract,The minimum inhibitory comcentration(MIC) and minimum bactericidal concentration(MBC) of the ethanol extract were0.65g/L and 0.85g/L,respectively.against S.aureus.Treatment of the extract at higher temperature,60℃ increased the sensitivity of the test of ganisms to the plant extract.Phytochemical analysis indicated that the plant possesses tannins,saponins as well as phenols.Concluslon:A scientific basis that the plant possesses antibacterial activity and it could be a probable source of therapeutic agent.