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Immunophenotypic Diagnosis of Leukemic B-Cell Chronic Lymphoproliferative Disorders Other Than Chronic Lymphocytic Leukemia

Alberto Órfão, Júlia Almeida, María Luz Sánchez, Jesús F. San Miguel

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Abstract

Leukemic B-cell chronic lymphoproliferative disorders (B-CLPD) are a relatively heterogeneous group of diseases, all of which exhibit a clonal expansion of mature-appearing B-lymphoid cells in the peripheral blood (PB). Both primary leukemias and the leukemic phase of primary lymphomas are included in this category (1) . Among the primary B-cell leukemias, chronic lymphocytic leukemia (CLL), prolymphocytic leukemia (PLL), and hairy cell leukemia (HCL) are usually considered; within the primary lymphomas, follicular lymphoma (FL), mantle cell lymphoma (MCL), marginal zone splenic lymphoma (MZSL), lymphoplasmacytic lymphoma (LPL), and the large B-cell lymphomas (LCLs) exhibit PB involvement more frequently (1) . These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

About this research paper

What this paper is about

Leukemic B-cell chronic lymphoproliferative disorders (B-CLPD) are a relatively heterogeneous group of diseases, all of which exhibit a clonal expansion of mature-appearing B-lymphoid cells in the peripheral blood (PB). Both primary leukemias and the leukemic phase of primary lymphomas are included in this category (1) . Among the primary B-cell leukemias, chronic lymphocytic leukemia (CLL), prolymphocytic leukemia (PLL), and hairy cell leukemia (HCL) are usually considered; within the primary lymphomas, follicular lymphoma (FL), mantle cell lymphoma (MCL), marginal zone splenic lymphoma (MZSL), lymphoplasmacytic lymphoma (LPL), and the large B-cell lymphomas (LCLs) exhibit PB involvement more frequently (1) . These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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OpenAlex reports 14 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Leukemic B-cell chronic lymphoproliferative disorders (B-CLPD) are a relatively heterogeneous group of diseases, all of which exhibit a clonal expansion of mature-appearing B-lymphoid cells in the peripheral blood (PB). Both primary leukemias and the leukemic phase of primary lymphomas are included in this category (1) . Among the primary B-cell leukemias, chronic lymphocytic leukemia (CLL), prolymphocytic leukemia (PLL), and hairy cell leukemia (HCL) are usually considered; within the primary lymphomas, follicular lymphoma (FL), mantle cell lymphoma (MCL), marginal zone splenic lymphoma (MZSL), lymphoplasmacytic lymphoma (LPL), and the large B-cell lymphomas (LCLs) exhibit PB involvement more frequently (1) . These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Key concepts: Chronic lymphocytic leukemia, Hairy cell leukemia, Prolymphocytic leukemia, Lymphoplasmacytic Lymphoma, Mantle cell lymphoma, Lymphoproliferative disorders, Medicine, Follicular lymphoma

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Immunophenotypic Diagnosis of Leukemic B-Cell Chronic Lymphoproliferative Disorders Other Than Chronic Lymphocytic Leukemia — Research Paper | ScholarLens