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Effect of vagotomy on the acid response to gastric distension

ROY M. PRESHAW

Open publisher page 4 citations

Abstract

Distension of the body of the stomach, in conscious dogs with vagally innervated antral pouches, caused an increase in gastric acid output, and an increase in antral motor activity. Truncal vagotomy inhibited the acid response to distension, but had no effect on the antral motor response. Denervation of the antral pouch by separating it from the main stomach caused little further diminution in the response.

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What this paper is about

Distension of the body of the stomach, in conscious dogs with vagally innervated antral pouches, caused an increase in gastric acid output, and an increase in antral motor activity. Truncal vagotomy inhibited the acid response to distension, but had no effect on the antral motor response. Denervation of the antral pouch by separating it from the main stomach caused little further diminution in the response.

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Available abstract

Distension of the body of the stomach, in conscious dogs with vagally innervated antral pouches, caused an increase in gastric acid output, and an increase in antral motor activity. Truncal vagotomy inhibited the acid response to distension, but had no effect on the antral motor response. Denervation of the antral pouch by separating it from the main stomach caused little further diminution in the response.

Key concepts: Distension, Antrum, Gastric distension, Vagotomy, Stomach, Denervation, Internal medicine, Pyloric Antrum

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