Design and Synthesis of 6 α-Corticosteroid Haptens and Their Bovine Serum Albumin(BSA) Conjugates
Pi Pi, Sun, Norihiro, Kobayashi
Abstract
Pi Pi, Sun, Norihiro, Kobayashi
Abstract
The site of attachment of protein carrier to corticosteroids has great influence on the specificity of produced antibody. In order to obtain highly specific and accurate antibodies for bioimmunoassay determination of cortisol, different tether lengths of 6α-corticosteroid haptens and their BSA conjugates were designed and synthesized.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
The site of attachment of protein carrier to corticosteroids has great influence on the specificity of produced antibody. In order to obtain highly specific and accurate antibodies for bioimmunoassay determination of cortisol, different tether lengths of 6α-corticosteroid haptens and their BSA conjugates were designed and synthesized.
Key concepts: Hapten, Bovine serum albumin, Conjugate, Antibody, Chemistry, Corticosteroid, Serum albumin, Transcortin