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2015•International Journal of Medical Science and Public HealthOpen access

Study of serum uric acid and creatinine in hypertensive disorders of pregnancy

Sapna Vyakaranam, Aparna Varma Bhongir, Dakshayani Patlolla, Rekha Chintapally

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Abstract

BACKGROUND: Renal dysfunction, increased xanthine oxidase activity and oxidative stress in placenta contributes to the elevated uric acid levels in preeclampsia (PE). OBJECTIVE: To determine serum uric acid and creatinine in hypertensive disorders of pregnancy and correlate with fetal outcome. MATERIALS AND METHODS: Pregnant women ≥32 weeks of gestation. Study population included 3 groups, 31 normotensive pregnant (NP) women as controls, 30 pregnant women with gestational hypertension (GH) and 30 with PE. RESULT: =0.87). CONCLUSION: Serum uric acid is a better diagnostic and predictive marker for PE and fetal outcome respectively.

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BACKGROUND: Renal dysfunction, increased xanthine oxidase activity and oxidative stress in placenta contributes to the elevated uric acid levels in preeclampsia (PE). OBJECTIVE: To determine serum uric acid and creatinine in hypertensive disorders of pregnancy and correlate with fetal outcome. MATERIALS AND METHODS: Pregnant women ≥32 weeks of gestation. Study population included 3 groups, 31 normotensive pregnant (NP) women as controls, 30 pregnant women with gestational hypertension (GH) and 30 with PE. RESULT: =0.87). CONCLUSION: Serum uric acid is a better diagnostic and predictive marker for PE and fetal outcome respectively.

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Available abstract

BACKGROUND: Renal dysfunction, increased xanthine oxidase activity and oxidative stress in placenta contributes to the elevated uric acid levels in preeclampsia (PE). OBJECTIVE: To determine serum uric acid and creatinine in hypertensive disorders of pregnancy and correlate with fetal outcome. MATERIALS AND METHODS: Pregnant women ≥32 weeks of gestation. Study population included 3 groups, 31 normotensive pregnant (NP) women as controls, 30 pregnant women with gestational hypertension (GH) and 30 with PE. RESULT: =0.87). CONCLUSION: Serum uric acid is a better diagnostic and predictive marker for PE and fetal outcome respectively.

Key concepts: Medicine, Uric acid, Creatinine, Preeclampsia, Internal medicine, Endocrinology, Gestation, Pregnancy

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