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CEA doubling time in relapsed cases of lung cancer.

Meinoshin Okumura, Yahiro Kotake, Kiyohiko In, Satoshi Sakai, Hirofumi Sueki, Hiroshi Katsura, Noboru Nakano, Senya Oshima, Masahiro Fukuoka, Tsutomu Yasumitsu

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Abstract

肺癌切除後再発例の内, CEA上昇例をもとにそのCEA doubling timeと再発部位の関係を検討したところ, 平均値は局所再発で165.2日, 肺転移で86.7日, 肺以外の遠隔転移で57.7日, 癌性心嚢炎で48.6日であり, 局所再発と肺転移, 局所再発と遠隔転移, 局所再発と癌性心嚢炎の間で有意差を認めた. また, CEA doubling timeと生存期間の間には正の相関関係を認め, CEA doubling timeは予後推定にも有用と思われた.

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Key concepts: Doubling time, Medicine, Lung cancer, Oncology, Biology, Cell, Genetics