1997Birkhäuser Boston eBooksRequires access

Eptastigmine: A Cholinergic Approach to the Treatment of Alzheimer’s Disease

Bruno P. Imbimbo

Open publisher page 9 citations

Abstract

Cholinesterase inhibitors have a well established role in the symptomatic treatment of patients with Alzheimer’s disease. However, clinical results obtained over the past 20 years have been contradictory. This is perhaps due to the poor systemic tolerability, short duration of action, unknown target Cholinesterase inhibition and tolerance following chronic use of current drugs. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

About this research paper

What this paper is about

Cholinesterase inhibitors have a well established role in the symptomatic treatment of patients with Alzheimer’s disease. However, clinical results obtained over the past 20 years have been contradictory. This is perhaps due to the poor systemic tolerability, short duration of action, unknown target Cholinesterase inhibition and tolerance following chronic use of current drugs. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Cholinesterase inhibitors have a well established role in the symptomatic treatment of patients with Alzheimer’s disease. However, clinical results obtained over the past 20 years have been contradictory. This is perhaps due to the poor systemic tolerability, short duration of action, unknown target Cholinesterase inhibition and tolerance following chronic use of current drugs. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Key concepts: Tolerability, Cholinesterase, Disease, Medicine, Cholinergic, Pharmacology, Neuroscience, Internal medicine

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