The Effects of Bojungikgi-tang on the Nasal Tissue in Allergic Rhinitis of Ovalbumin0inhalation Rats.
Kim Jong-sung, Sim SungYong, Um Yu-sik, Nam Hae-jeong, Kyung-Jun Kim
Abstract
Kim Jong-sung, Sim SungYong, Um Yu-sik, Nam Hae-jeong, Kyung-Jun Kim
Abstract
Allergic rhinitis is an allergic reaction characterized by sneezing, coughing, itchy nose, mouth and throat, congestion and/or nasal discharge. The offending allergens are usually pollens, molds, dust mites and animal allergens. We aimed to observe inhibitory effects of Bojungikgi-tang on incerase of the number of eosinophil and neutrophil, and protective effects of nasal mucosal tissue in the allergic rhinitis. 1. In Inhibitory Effect of Bojungikgi-tang on Increase of the number of Eosinophil in Serum, Bojungikgi-tang showed significant effects.(p〈0.05) 2. In Inhibitory Effect of Bojungikgi-tang on Increase of the number of Neutrophil in Serum, Bojungikgi-tang showed significant effects.(p〈0.05) 3. In histopathologic change of nasal mucosal tissue, Bojungikgi-tang showed significant protective effects. Depending upon above results, it is considered that Bojungikgi-tang has the inhibitory effects on the process of allergic rhinitis and that it could be used in reliving patients of the symptoms caused by allergic rhinitis.
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Allergic rhinitis is an allergic reaction characterized by sneezing, coughing, itchy nose, mouth and throat, congestion and/or nasal discharge. The offending allergens are usually pollens, molds, dust mites and animal allergens. We aimed to observe inhibitory effects of Bojungikgi-tang on incerase of the number of eosinophil and neutrophil, and protective effects of nasal mucosal tissue in the allergic rhinitis. 1. In Inhibitory Effect of Bojungikgi-tang on Increase of the number of Eosinophil in Serum, Bojungikgi-tang showed significant effects.(p〈0.05) 2. In Inhibitory Effect of Bojungikgi-tang on Increase of the number of Neutrophil in Serum, Bojungikgi-tang showed significant effects.(p〈0.05) 3. In histopathologic change of nasal mucosal tissue, Bojungikgi-tang showed significant protective effects. Depending upon above results, it is considered that Bojungikgi-tang has the inhibitory effects on the process of allergic rhinitis and that it could be used in reliving patients of the symptoms caused by allergic rhinitis.
Key concepts: Eosinophil, Medicine, Nose, Inhibitory postsynaptic potential, Allergy, Mucous membrane of nose, Immunology, Throat