2008•The Korean Journal of MicrobiologyRequires access

Genetic Distribution of Human Noroviruses Detected from Acute Gastroenteritis Patients in Seoul

Eun-Jeung Kim, Sang-Hun Park, Miok Song, Moo‐Sang Kim, Minyoung Kim, Doo‐Sung Cheon, Hae-Sook Jeong, Chul‐Joong Kim

Abstract

Fecal specimens from acute gastroenteritis in Seoul from 2004 to 2007 were collected and then tested for the presence of norovirus by RT-PCR. 258 noroviruses were subjected to be futher characterized to sequencing analysis. The sequencing analysis showed that thirteen genotypes were detected (GII.1, GII.2, GII.3, GII.4, GII.5, GII.6, GII.8, GII.10, GII.l2, GII.13, GII.l5, GII.l6, GII.l7) and predominant genotype was GII.4 (76.7%) in the cases of norovirus detected sporadic acute gastroenteritis in Seoul. By this molecular investigation, genotypic distribution associated with norovirus infections will be used for control and prevention of norovirus related diseases.

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Key concepts: Norovirus, Acute gastroenteritis, Genotype, Virology, Feces, Biology, Medicine, Microbiology