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2012•Journal of Pre-Clinical and Clinical ResearchOpen access

Severe hyponatremia due to inappropriate antidiuretic hormone secretion – a case report

Agnieszka Witczak, Andrzej Prystupa, Andrzej Biłan, Andrzej Ignatowicz, Katarzyna Kwaśniewska, Agata Rękas-Wójcik, Maciej Błaszczuk, Jerzy Mosiewicz

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Abstract

Inappropriate antidiuretic hormone secretion syndrome (SIADH) is the most common cause of normovolemic hypotonic hyponatremia in hospital settings. The article describes the case of a female patient admitted to hospital because of life threatening hyponatremia, probably due to SIADH. Laboratory tests and imaging were made to exclude possible causes of inadequate ADH release. 3% saline infusion together with dietary salt supplementation and fluid restriction were applied to restore sodium balance. The patient was successfully treated and discharged home without evident neurological deficits.

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What this paper is about

Inappropriate antidiuretic hormone secretion syndrome (SIADH) is the most common cause of normovolemic hypotonic hyponatremia in hospital settings. The article describes the case of a female patient admitted to hospital because of life threatening hyponatremia, probably due to SIADH. Laboratory tests and imaging were made to exclude possible causes of inadequate ADH release. 3% saline infusion together with dietary salt supplementation and fluid restriction were applied to restore sodium balance. The patient was successfully treated and discharged home without evident neurological deficits.

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Available abstract

Inappropriate antidiuretic hormone secretion syndrome (SIADH) is the most common cause of normovolemic hypotonic hyponatremia in hospital settings. The article describes the case of a female patient admitted to hospital because of life threatening hyponatremia, probably due to SIADH. Laboratory tests and imaging were made to exclude possible causes of inadequate ADH release. 3% saline infusion together with dietary salt supplementation and fluid restriction were applied to restore sodium balance. The patient was successfully treated and discharged home without evident neurological deficits.

Key concepts: Hyponatremia, Antidiuretic, Fluid restriction, Syndrome of inappropriate antidiuretic hormone secretion, Medicine, Hormone, Hypertonic saline, Saline

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